Augmented renal clearance. An unnoticed relevant event
نویسندگان
چکیده
منابع مشابه
Augmented Renal Clearance in Critical Illness: An Important Consideration in Drug Dosing
Augmented renal clearance (ARC) is a manifestation of enhanced renal function seen in critically ill patients. The use of regular unadjusted doses of renally eliminated drugs in patients with ARC might lead to therapy failure. The purpose of this scoping review was to provide and up-to-date summary of the available evidence pertaining to the phenomenon of ARC. A literature search of databases o...
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BACKGROUND Recent evidence suggests that current antimicrobial dosing may be inadequate for some critically ill patients. A major contributor in patients with unimpaired renal function may be Augmented Renal Clearance (ARC), wherein urinary creatinine clearance exceeds that predicted by serum creatinine concentration. We used pharmacokinetic data to evaluate the diagnostic accuracy of a recentl...
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Suppose f = Pk `=1 w`f`, where w1, w2, . . . , wk are positive constants, Pk `=1 w` = 1, and f1, f2, . . . , fk are real-valued and Riemann integrable functions on [−π, π]. Let λ (`) 1n ≤ λ (`) 2n ≤ · · · ≤ λ `) nn be the eigenvalues of the Hermitian Toeplitz matrices T (`) n = [t (`) r−s] n r,s=1, where t (`) r = 1 2π R π −π ef`(x) dx , and let λ1n ≤ λ2n ≤ · · · ≤ λnn be the eigenvalues of Tn ...
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There is little data available to guide amoxicillin-clavulanic acid dosing in critically ill children. The primary objective of this study was to investigate the pharmacokinetics of both compounds in this pediatric subpopulation. Patients admitted to the pediatric intensive care unit (ICU) in whom intravenous amoxicillin-clavulanic acid was indicated (25 to 35 mg/kg of body weight every 6 h) we...
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The aim of this study was to evaluate the effect of augmented renal clearance (ARC) on vancomycin serum concentrations in critically ill patients. This prospective, single-centre, observational, cohort study included 93 consecutive, critically ill septic patients who started treatment that included vancomycin by continuous infusion, admitted over a 2-year period (March 2006 to February 2008). A...
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ژورنال
عنوان ژورنال: Science Progress
سال: 2021
ISSN: 0036-8504,2047-7163
DOI: 10.1177/00368504211018580